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Does Quinine work for leg cramps? Quinine sulfate at a dose of 200–300 mg at night has been used for many years to treat nocturnal leg cramps. Usually idiopathic, these muscle cramps are common, particularly in older patients. Quinine may help by decreasing the excitability of the motor end-plate and increasing the muscle refractory period.
Can you overdose on tonic water? Quinine, when found in small doses in tonic water, is safe to consume. The first tonic waters contained powdered quinine, sugar, and soda water. Today, people sometimes drink tonic water to treat nighttime leg cramps associated with circulatory or nervous system problems. However, this treatment is not recommended.
Does tonic water relieve leg cramps? Q. It's been suggested that drinking 2 to 3 ounces of tonic water before bedtime can prevent leg cramps at night. A. Tonic water —and the quinine it contains—have been promoted for preventing leg cramps for decades despite the lack of evidence that they are effective.
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